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Westwood Cardiology regular participates in national and international clinical trials to help ensure that our patients have access to the most current therapies available.


Current Clinical Trials:


    ON TARGET/TRANSCEND is a large multi-center international study evaluating whether the combination of an ACE (angiotensin converting enzyme) inhibitor and ARB (angiotensin receptor blocker) is more effective than an ACE or ARB alone in reducing the risk of heart attack, stroke, heart failure or death in patients with heart disease or peripheral vascular disease.


HF ACTION is a large multi-center NIH study evaluating whether exercise can reduce mortality and hospitalization in patients with congestive heart failure.


IMPROVE HF is the largest heart failure quality improvement outpatient registry ever undertaken, that is designed to assess and improve heart failure treatment practices.


INTER-TRIAL is an NIH infrastructure project that we are participating with in coordination with Columbia University that is evaluating networks for optimal clinical research.


     CLOSURE I is an FDA-approved study to determine if non-surgical patch closure of a congenital heart defect (a patent foramen ovale or hole in the atrial wall) can prevent future stroke in victims of unexplained stroke at a young age.

Studies Concluded:

AFFIRM established optimal treatment regiments for patients with atrial fibrillation


ACES evaluated the role of inflammation in patients with coronary artery disease


ELITE the first study to demonstrate the utility of angiotensin receptor blockers in elderly patients with congestive heart failure


RELY is an international multicenter trial evaluating the effectiveness of a novel blood thinner, dabigatran (an oral direct thrombin inhibitor) vs. coumadin in patients with atrial fibrillation. This completed study led to the release of the new anticoagulant Pradaxa (dabigatran) in 2010.


SCD-HEFT helped establish the utility of defibrillators in patients with ischemic and nonischemic cardiomyopathies

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